What question did this study set out to answer?

To evaluate the effectiveness of bupivacaine and articaine for pain management in mandibular fracture surgeries.

February 16, 2026Open Access

Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study

APAjay K. PillaiPeople’s University DSDheeraj SharmaPeople’s University NJNeha JainPeople’s University

Key Points

To evaluate the effectiveness of bupivacaine and articaine for pain management in mandibular fracture surgeries.
In vivo study comparing 0.5% bupivacaine and 4% articaine.
Participants included 40 patients undergoing surgical management of mandibular fractures.
Analgesic effects were measured via rescue analgesia timing.
Bupivacaine patients required rescue analgesia significantly later than those receiving articaine (10.40 h vs. 7.30 h).
Mean difference of 3.10 h in analgesic requirement indicates meaningful improvement.
42% delay in analgesic requirement suggests better postoperative pain management.

Abstract

A BSTRACT Aim: To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures. Material and Method: The sample consisted of 40 participants, who required management of mandibular fractures. Results: Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h ( P < 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.

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