Delayed neurological events after mumps vaccination: implications for surveillance and clinical recognition

Key Points

• This research aims to highlight delayed neurological complications following mumps vaccination and suggest improvements in vaccine surveillance.
• Report a case of febrile status epilepticus and aseptic meningitis post-vaccination.
• Identify vaccine strain in cerebrospinal fluid using reverse transcription-PCR and sequencing.
• Assess current vaccine safety surveillance practices and propose enhancements.
• A previously healthy infant experienced status epilepticus and aseptic meningitis 23 days after vaccination.
• The vaccine strain was successfully identified in the cerebrospinal fluid.
• Recommendations for longer surveillance periods and improved clinician awareness were suggested.

Abstract