What question did this study set out to answer?

To examine the symptoms, causes, and risk factors associated with unilateral acute non-granulomatous anterior uveitis in a Nepali population.

February 19, 20260 citations

Pattern of Symptoms, Aetiologies, and Associated Risk Factors of Unilateral Acute Non-granulomatous Anterior Uveitis Cases Presenting in a Tertiary Eye Institute of Nepal.

AMAnu Manandhar VGVidisha GuptaKurukshetra University APAraniko PandeyCivil Service Hospital

Key Points

To examine the symptoms, causes, and risk factors associated with unilateral acute non-granulomatous anterior uveitis in a Nepali population.
Analyzed cases of unilateral NGAU at a tertiary eye institute in Nepal
Documented symptoms such as pain, redness, photophobia, and watering
Evaluated demographic factors, including smoking status and HLA-B27 gene positivity
Smoking is strongly associated with unilateral NGAU cases
HLA-B27 gene positivity found in slightly over 50% of cases
Symptoms include pain, redness, photophobia, decreased vision, and watering
Relapse of symptoms predominantly occurs during summer months

Abstract

Unilateral NGAU in Nepali population is strongly associated with present or past smoking, not strongly associated with stress factor, relapses mostly in summer season, and shows HLA-B27 gene positivity in slightly >50% population. Other than pain, redness, photophobia, and decreased vision, watering can also be one of the presenting symptoms of NGAU cases.

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