Does increasing warfarin use correlate with an increased incidence of anticoagulant-associated intracerebral hemorrhage?
The incidence of anticoagulant-associated intracerebral hemorrhage increased five-fold during the 1990s due to rising warfarin use, reaching a frequency comparable to subarachnoid hemorrhage.
The incidence of anticoagulant-associated intracerebral hemorrhage quintupled in our population during the 1990s. The majority of this change can be explained by increasing warfarin use. Anticoagulant-associated intracerebral hemorrhage now occurs at a frequency comparable to subarachnoid hemorrhage.
Flaherty et al. (Mon,) studied this question.