What question did this study set out to answer?

The study aimed to evaluate the immediate effects of Pain Neuroscience Education on pain and psychological factors in physiotherapy students with chronic non-specific low back pain.

February 22, 2026Open Access

Immediate effects of pain neuroscience education in physiotherapy students with chronic non-specific low back pain: a single arm pre–post intervention study

Key Points

The study aimed to evaluate the immediate effects of Pain Neuroscience Education on pain and psychological factors in physiotherapy students with chronic non-specific low back pain.
Conducted a single-arm, pre-post intervention study
Included 79 undergraduate physiotherapy students with chronic non-specific low back pain
Administered a single 70-minute Pain Neuroscience Education session
Utilized scales to measure pain intensity, pain knowledge, catastrophizing, and kinesiophobia before and after the session
Significant decrease in pain intensity measured by the NPRS (p = 0.004)
Significant decrease in kinesiophobia measured by the TSK (p = 0.034)
Significant increase in pain knowledge measured by the rNPQ (p < 0.001)
No significant change in pain catastrophizing measured by the PCS (p = 0.312)

Abstract

Our study aimed to investigate the immediate effects of a single session of Pain Neuroscience Education (PNE) on pain intensity, pain knowledge, pain catastrophizing, and kinesiophobia in undergraduate physiotherapy students with chronic non-specific low back pain (CNSLBP). This prospective, single-arm, pre-post intervention study was conducted with 79 undergraduate physiotherapy students with CNSLBP. Participants received a single, 70-minute PNE session, administered by an expert physiotherapist with a PNE certification. Before and immediately after the intervention measurements were made using the Numeric Pain Rating Scale (NPRS), the Revised Pain Neurophysiology Questionnaire (rNPQ), the Pain Catastrophizing Scale (PCS), and the Tampa Scale of Kinesiophobia (TSK). After PNE, NPRS (p = 0.004; d = 0.131) and TSK (p = 0.034; d = 0.253) scores decreased statistically significantly, while the rNPQ score increased significantly (p < 0.001; d = 0.505). However, there was no statistically significant improvement in the PCS score (p = 0.312; d = 0.124). This study suggests that a single PNE session was associated with immediate improvements in pain knowledge and immediate reductions in pain intensity and kinesiophobia in undergraduate physiotherapy students with CNSLBP. Overall, PNE may be incorporated into rehabilitation as a useful educational primer to support pain-related outcomes, but it should be complemented by other interventions to achieve clinically meaningful reductions in pain intensity. ClinicalTrials.gov identifier: NCT07249710; retrospectively registered on 18 November 2025.

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