A Modular Approach toward 5,6,7,8-functionalized Acepleiadylene derivatives

Key Points

• The aim is to develop a modular synthesis method for acepleiadylene derivatives.
• Developed a synthesis method using Suzuki coupling of biphenyl compounds with acenaphthenylboronic acid.
• Applied DDQ oxidation for the synthesis of derivatives.
• Successfully synthesized the first acepleiadylene derivatives using the innovative approach.
• Improved efficiency and modularity in the synthesis process.