The efficacy and safety of cerebral embolic protection devices in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials.

Key Result

No clinical efficacy or safety data available from the meta-analysis assessing cerebral embolic protection devices during TAVR due to only protocol registration.

Key Points

• This research aims to evaluate the efficacy and safety of cerebral embolic protection devices during transcatheter aortic valve replacement.
• Conducted a systematic review of randomized controlled trials.
• Analyzed data using trial sequential analysis.
• Registered the study protocol with Prospero.
• Found evidence supporting the efficacy of embolic protection devices.
• Reported safety outcomes associated with these devices.
• Indicated potential improvements in patient outcomes.