The analysis of the thermoreceptor gene (rs322937) was carried out in 15 population samples (1503 people) belonging to different language groups living in the regions of the Altai-Sayan Highlands, Western Siberia, the Far East and Canada. The highest frequency of the rare allele was found in the Yakuts (42.9%), and the lowest in the Eskimos (10.7%) and Evenks (10.8%). Deviations from the Hardy-Weinberg equilibrium were found in the population of Siberian Tatars. The greatest interpopulation differences were found between the Yakuts and Evenks, and the smallest between the Kazakhs, Telengits and Khakass, Telengits and Tatars, Khakass and Nanai, Tuvans and Northern Altaians. Transassociation of polymorphic loci of the , , and genes was carried out using the regression analysis method. Of the six pairs, a positive correlation was found in 3: , and . Thus, the gene studied by us is positively correlated with and and negatively with . The results obtained may indicate different selective pressure in different geographical areas determined by climatic factors.
M.A. Gubina (Wed,) studied this question.