A Direct Route to Ynones: Pd-Catalyzed Sonogashira Carbonylative Coupling of Ethers with Alkynes via C-O Cleavage

Key Points

• The study aims to develop a catalytic method utilizing benzylic ethers in coupling reactions.
• Develops a palladium/copper cocatalyzed pathway.
• Utilizes benzylic ethers as coupling partners.
• Assesses substrate scope for the reaction.
• The reaction accommodates a wide range of substrates.