What does this research mean for the field?

Left atrial appendage closure can treat acute perforation by sealing the defect and the LAA, potentially avoiding the need for surgery. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate an intervention for managing left atrial appendage perforation during implantation procedures.

February 27, 2026Open Access

Percutaneous Rescue With Sequential Second-Device Usage for Left Atrial Appendage Perforation During Amulet Implantation

Key Result

Left atrial appendage closure can treat acute perforation by sealing the defect and LAA, potentially avoiding the need for surgery.

Key Points

The aim is to evaluate an intervention for managing left atrial appendage perforation during implantation procedures.
Utilized a novel percutaneous technique
Employed sequential second-device usage
Focused on a case of left atrial appendage perforation during implantation
Successfully sealed the perforation with the second device
Reduced need for invasive surgical procedures
Demonstrated effective management of acute complications

Structured PICO

Can percutaneous rescue with sequential second-device usage effectively treat acute left atrial appendage perforation during Amulet implantation?

Population

Patients experiencing left atrial appendage perforation during Amulet implantation

Intervention

Percutaneous rescue with sequential second-device usage (Left Atrial Appendage Closure)

Outcome

Sealing both the defect and the left atrial appendagesafety

Sequential second-device usage during LAAC can serve as a percutaneous rescue strategy for acute LAA perforation, potentially averting the need for surgical intervention.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

LAAC itself can treat acute perforation by sealing both the defect and the LAA before considering surgery.