The accelerating impacts of climate change continue to challenge global agriculture, increasing the need for adaptive and sustainable technological solutions. In this context, Unmanned Aerial Vehicles (UAVs) have evolved from experimental tools to key components of precision agriculture, offering advanced capabilities for monitoring, diagnosis, and targeted intervention. This Research Topic explores how UAVs, combined with remote sensing, AI, and operational strategies, can advance climate-smart agriculture. The topic focuses on innovative technologies and UAV applications in precision agriculture for mitigating climate change, highlighting recent advancements.The four contributions in this collection illustrate UAVs' potential to improve resource-use efficiency, enhance plant protection, enable early detection of biotic stress, and support scalable, data-driven decision-making. Together, these studies underline both the versatility of UAV technologies and the need for continued innovation to address environmental variability, operational challenges, and integration with complementary sensing platforms.Regarding UAV for spraying, the: operational variability and deposition efficiency,
Martínez-Peña et al. (Wed,) studied this question.