The interaction of (3-methylfurazanyl)- and (3-aminofurazanyl)amidrazones with 1,2-dicarbonyl compounds (ninhydrin, glyoxal and benzyl) was studied. It was shown that upon using glyoxal, only acyclic products of dimeric structure were formed, while the introduction of other studied 1,2-dicarbonyl compounds into the reaction led to the target (1,2,4-triazin-3-yl)furazans. The structure of the obtained products was confirmed by IR and NMR spectroscopy and X-ray structural analysis. The synthesized biheterocyclic structures are of interest as a platform for the design of pharmacologically active compounds with different spectra of action.
A.A. Larin (Wed,) studied this question.