What question did this study set out to answer?

Evaluate the role of near-infrared spectroscopy (NIRS) in predicting outcomes during and after cardiopulmonary resuscitation (CA).

March 1, 2026Open Access

Near-infrared spectroscopy (NIRS) during and after cardiopulmonary resuscitation: A systematic review and meta-analysis

Key Points

Evaluate the role of near-infrared spectroscopy (NIRS) in predicting outcomes during and after cardiopulmonary resuscitation (CA).
Conducted a systematic review and meta-analysis of studies using NIRS in CA situations.
Analyzed real-time rSO2 values during and after CA to assess predictive power for successful resuscitation.
Examined the association of post-ROSC rSO2 values with neurological outcomes.
Higher rSO2 values during CA correlate with increased rates of return of spontaneous circulation (ROSC).
Delta rSO2 values predicted outcomes better than static values, although retrospective calculations are limited.
Initial rSO2 values after ROSC are linked to better neurological outcomes.

Abstract

Higher rSO2 values during CA are consistently associated with increased rates of ROSC, with delta rSO2 values having the highest predictive power. However, from a practical point of view, retrospectively calculating delta values poses a significant limitation which could be overcome by rather using real-time trends. Also, the implementation of NIRS in postresuscitation care could be an additional component of early multimodal prognostication after CA as we showed that higher initial rSO2 values after ROSC are associated with a favourable neurological outcome.

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Cite This Study

Kornfehl et al. (Thu,) studied this question.

synapsesocial.com/papers/69a3d6eaec16d51705d2da50 https://doi.org/https://doi.org/10.1016/j.aucc.2026.101534

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