Radiation Therapy Combined with Immunotherapy Before Radical Cystectomy in Locally Advanced Bladder Cancer: A Prospective, Single-arm, Multicenter, Phase 2 Trial (RACE-IT)

Key Points

• This trial aimed to evaluate the safety and feasibility of neoadjuvant radioimmunotherapy before radical cystectomy in bladder cancer.
• Prospective, single-arm, multicenter trial
• Participants with locally advanced bladder cancer
• Neoadjuvant treatment with radiation therapy and immunotherapy prior to surgery
• Successfully met the primary endpoint of feasibility
• Demonstrated safety of the combined treatment approach