Frailty in ambulatory HFpEF patients is linked to higher adverse outcomes risk, but this association weakens after adjusting for congestion and anemia/iron markers.
Does frailty predict adverse outcomes in patients with ambulatory heart failure with preserved ejection fraction?
The association between frailty and adverse outcomes in HFpEF is largely explained by shared pathophysiologic factors like congestion and anemia, rather than being an independent prognostic factor.
Absolute Event Rate: 0% vs 0%
Frailty is common in ambulatory HFpEF. In unadjusted models, frailty is associated with higher risk, but this is attenuated after accounting for congestion and anemia/iron markers, supporting a shared pathophysiologic pathway linking frailty and HFpEF rather than an independent prognostic effect.
Tanacli et al. (Thu,) reported a other. Frailty in ambulatory HFpEF patients is linked to higher adverse outcomes risk, but this association weakens after adjusting for congestion and anemia/iron markers.