Effect on neonatal outcomes of maintenance of maternal blood pressure targets with noradrenaline after spinal anaesthesia for caesarean delivery: a multicentre, randomised, controlled trial.

Key Points

• The aim is to evaluate the impact of maintaining maternal blood pressure targets during caesarean delivery on neonatal and maternal outcomes.
• Randomised controlled trial across multiple centres
• Subjects received boluses of noradrenaline
• Systolic blood pressure targets set at >90% or >80% of baseline
• Higher systolic blood pressure (>90% of baseline) reduced neonatal acidaemia
• Maintaining higher blood pressure decreased maternal hypotension
• Fewer cases of maternal nausea and vomiting were reported