What does this research mean for the field?

GAD65 and ZnT8 positive autoimmune diabetes can occur in patients with Wiskott-Aldrich Syndrome (WAS). Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

What question did this study set out to answer?

This case report aims to describe an instance of autoimmune diabetes in a patient with Wiskott-Aldrich Syndrome.

March 1, 2026

A Novel Autoimmune Presentation of Wiskott-Aldrich Syndrome: Type 1 Diabetes.

Key Points

This case report aims to describe an instance of autoimmune diabetes in a patient with Wiskott-Aldrich Syndrome.
Case report of a single patient
Diagnostic testing for autoimmune markers
Assessment of clinical history
Patient tested positive for GAD65 and ZnT8 antibodies
Identified as the first recorded instance of autoimmune diabetes in WAS
Expanded understanding of autoimmune conditions in WAS patients

Abstract

To our knowledge, this is the first reported case of GAD65 and ZnT8 positive autoimmune diabetes in a patient with WAS. This case expands the spectrum of autoimmune disease associated with WAS and underscores the importance of maintaining a high index of suspicion for atypical autoimmune presentations in patients with WAS.

Bookmark

A Novel Autoimmune Presentation of Wiskott-Aldrich Syndrome: Type 1 Diabetes.

Key Points

Abstract

Cite This Study