The efficient removal and selective recognition of pharmaceutical residues from aquatic systems remains a critical challenge in green analytical chemistry. Here, we report magnetic molecularly imprinted polymers (DES-MMIPs) synthesized using a deep eutectic solvent (DES; choline chloride/methacrylic acid) as a green functional monomer for targeted adsorption and detection of ibuprofen (IBP). Vinyl-modified Fe 3 O 4 nanoparticles serve as magnetic supports in a precipitation polymerization system. The resulting material exhibits a rough surface with well-defined imprinted cavities and sufficient magnetic responsiveness (saturation magnetization = 6.29 emu·g -1 ). Under optimized conditions, DES-MMIPs achieve an IBP adsorption capacity of 77.68 mg·g -1 -1.94 times that of non-imprinted polymers-reaching equilibrium within 80 min. Adsorption follows the Langmuir model (Q max = 151.52 mg·g -1 ) and pseudo-second-order kinetics (R 2 = 0.9820), consistent with monolayer chemisorption. DES-MMIPs show high selectivity, maintain performance in the presence of coexisting ions and humic acid, and retain 96.6% capacity over five adsorption–desorption cycles. This work establishes a sustainable molecular imprinting platform based on DES monomers for efficient extraction and monitoring of trace organic pollutants in complex aqueous environments.
Feng et al. (Fri,) studied this question.