Background: Prameha is described in Ayurveda as a Mutratipravrutta Vyadhi, characterized by Prabhuta Mutra and Avila Mutra. It is considered a Daruna Vyadhi due to the involvement of Tridosha, affliction of Basti, Mahamarmasthana and its association with multiple Upadravas. The condition bears close resemblance to Type II Diabetes Mellitus described in modern medicine. Ayurveda offers a holistic approach through numerous classical formulations including Kashaya, Ghrita, Vati and Gutika described in the context of Prameha Chikitsa, aiming at restoring Dosha, Dhatu, and Agni balance. Haridradi Taila mentioned as Pramehanam Vimshati Jayeth in Yogaratnakara is taken up for study in the management of Prameha vis-a-vis Type II Diabetes mellitus. Objectives: 1]To compare the efficacy of Haridradi Taila and Haridradi Kashaya in Yoga Basti and internal administration of Haridradi Kashaya in Prameha. 2]To evaluate the efficacy of Haridradi Taila and Haridradi Kashaya in Yoga Basti in Prameha. 3]To evaluate the efficacy of internal administration of Haridradi Kashaya in Prameha. Method: It was a controlled clinical study involving two groups, Group A and Group B each consisting of 20 patients. For Group A, Yoga Basti followed by internal administration of Haridradi Kashaya for next 30 days. Total duration 38 days. For Group B, internal administration of Haridradi Kashaya for 30 days. Total duration 30 days. Result: Basti therapy in Group A produced slight improvements in clinical symptoms such as Kshudadikya, Pipasadikya, and Prabhutamutrata along with remarkable changes in fasting urine sugar levels. However, FBS and PPBS showed comparatively lesser improvement. The overall therapeutic efficacy was significantly higher in Group A (37.14%) compared to Group B (15.03%). This indicates that the intervention in Group A resulted in a more comprehensive and effective management in Prameha.The present study establishes that Haridradi Yoga Basti provides marked efficacy in the management of Prameha compared to Shamanoushadi. Haridradi Yoga Basti not only produced relief in the cardinal symptoms such as Prabhutamutrata, Kshudadhikya, Pipasadhikya but also showed reduction in FUS and PPUS.
Pooja I. M. M.*1, Sanjay Kumar M. D.2, Anantha Desai3 (Sun,) studied this question.