Ankaferd Blood Stopper is a medicine gained from five types of plants used in traditional Turkish medicine. It can stop different types of bleeding in a short time. The study aims to determine the impact of ABS on the gastrointestinal system and to test its reliability. Four groups were created with Wistar albino rats. (Control, ABS local application, ABS-doped wound dressing, ABS non-doped wound dressing, n:6). A 15x15 millimeter wound was formed on the back of each rat, and the healing processes were closely followed. The investigation was terminated by sacrificing the rats by cervical dislocation on the 14th day. Stomach and small intestine tissues pulled out from mice were moved to 10% formaldehyde before the xylene and alcohol series. After routine histological methods, the tissues were dyed with hematoxylin-eosin and examined under light and electron microscopy. Mean stomach (p: 0.01) and small intestine weights (p: 0.02) increased in ABS-applied groups. The histopathological structure of the stomach tissue was normal in the ABS-applied groups. The profile of the tunica muscularis and submucosa were regular, and there was no degeneration. No atrophy or rupture was observed in the villi. Because ABS does not reason lesions in the stomach and small intestine, ABS may be a safe haemostatic agent option in the gastrointestinal tract. Further investigation is required to evaluate the impacts of prolonged ABS usage.
Sensoy et al. (Sat,) studied this question.