Small Airways Disease Adversely Impacts the Response to Biologic Therapies in Severe Asthma

Key Points

• This research examines how small airways disease affects responses to biologic treatments in severe asthma patients.
• Real-world cohort analysis
• Assessment of baseline small airways disease via oscillometry
• Evaluation of response to biologic therapy
• Baseline small airways disease is linked to lower response rates to biologic therapies
• Findings suggest using oscillometry can identify at-risk patients