What question did this study set out to answer?

The aim is to examine the prevalence and molecular characteristics of resistance genes in imipenem-non-susceptible UPEC isolates.

March 2, 2026Open Access

Prevalence and Molecular Characterization of β-Lactamase and Quinolone Resistance Genes in Imipenem-Non-Susceptible Uropathogenic Escherichia coli (UPEC) Isolates

Key Points

The aim is to examine the prevalence and molecular characteristics of resistance genes in imipenem-non-susceptible UPEC isolates.
Analyzed uropathogenic Escherichia coli isolates for resistance genes
Characterized the molecular structures of β-lactamase and quinolone resistance genes
Evaluated the correlation between different resistance determinants
A high prevalence of β-lactamase and qnr resistance genes was detected
The predominant genes were blaTEM and qnrB
Multiple resistance genes co-occurred in B2 isolates

Abstract

A high prevalence of β-lactamase and qnr determinants was observed among imipenem-non-susceptible UPEC, primarily driven by blaTEM and qnrB, frequently detected in B2 isolates. The co-occurrence and correlation of multiple resistance genes highlight the complexity of resistance architectures and underscore the need for ongoing molecular surveillance and strengthened antimicrobial stewardship to limit the dissemination of resistant UPEC.

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Cite This Study

Kara et al. (Mon,) studied this question.

synapsesocial.com/papers/69a52de5f1e85e5c73bf10ca https://doi.org/https://doi.org/10.31083/fbl48045

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