Morning urinary calcium/creatinine ratio as a sex-specific screening tool for detecting hypercalciuria in hypoparathyroidism

Key Points

• To determine sex-specific cut-off values of urinary calcium/creatinine ratio for detecting hypercalciuria in hypoparathyroidism.
• Propose a cut-off of 0.31 mmol/mmol for male patients as a surrogate for hypercalciuria.
• Identify a cut-off of 0.25 mmol/mmol for female patients as a screening tool.
• The proposed cut-off of 0.31 mmol/mmol effectively distinguishes hypercalciuria in males.
• In females, the 0.25 mmol/mmol cut-off is insufficient for reliable differentiation but suggests further testing.