The dynamic changes of serum levels of PD-1/PD-L1 correlate with the therapeutic effectiveness of antibiotics in patients with sepsis.

Key Points

• The research aims to explore the relationship between serum levels of PD-1/PD-L1 and the effectiveness of antibiotic treatment in sepsis.
• Observed serum levels of sPD-1 and sPD-L1 in patients with Enterobacteriaceae sepsis.
• Monitored changes in serum levels during antibiotic therapy.
• Analyzed the correlation between serum levels and treatment responses.
• Serum levels of sPD-1 and sPD-L1 were significantly elevated in patients with sepsis.
• These serum levels decreased dynamically in patients who responded to antibiotic therapy.
• Data indicates potential use of PD-1/PD-L1 levels as prognostic biomarkers.