Mechanistic and systemic perspectives on tumour necrosis factor-like weak inducer of apoptosis in pemphigus vulgaris

Key Points

• TWEAK-targeted strategies may enhance therapeutic options for pemphigus vulgaris patients in the future.
• Critical roles of neutrophil extracellular traps and intracellular signalling pathways are emphasized throughout the analysis.
• The study explores systemic and mechanistic perspectives on TWEAK in the context of immune response.
• Incorporating these perspectives could significantly impact future treatment methodologies for pemphigus vulgaris.