Urinary metabolites of 1,3-butadiene, benzene and toluene and colorectal cancer incidence: a clinical case–control study

Key Points

• Colorectal cancer incidence is associated with elevated urinary metabolites from 1,3-butadiene, benzene, and toluene.
• Participants in the study displayed significant differences in metabolite levels, especially those diagnosed with cancer.
• Observational analysis of urinary metabolites focused on individuals with varying colorectal cancer status, aiding in understanding environmental influences.
• Findings imply that monitoring urinary metabolites may help assess cancer risk linked to environmental toxins.