N‑acetylcysteine for post-ERCP pancreatitis prophylaxis: A systematic review and meta-analysis

Key Points

• N-acetylcysteine shows promise in reducing post-ERCP pancreatitis incidence.
• The meta-analysis includes data from multiple studies indicating efficacy at various doses.
• Observational analysis of diverse trial data demonstrates significant reduction in pancreatitis risks.
• Further validation needed in larger trials to confirm effectiveness and safety in clinical practice.