Surgical treatment of recurrent glioblastoma: a multicenter perspective from the Italian society of neurosurgery (SINch®) and a systematic review

Key Points

• Recurrent glioblastoma patients experience varied outcomes based on surgical treatment approaches, and nuances exist in intervention effectiveness.
• Key evidence reveals that specific surgical techniques can lead to significant survival differences in patients, with multifaceted factors influencing results.
• Analysis from multiple centers contributes to a comprehensive understanding of recurrent glioblastoma, focusing on neurosurgical interventions and patient selection criteria for optimal care.
• Findings support the need for standardized surgical protocols and further studies to assess long-term effects of treatment in recurrent glioblastoma cases.