Molecular docking and dynamics reveal potential galactagogue mechanism of Breynia patens via D2R, OXTR, and TRβ modulation

Key Points

• Breynia patens may enhance lactation through modulation of d2r, oxtr, and trβ pathways.
• Key findings suggest a significant interaction score of 93.2 for D2R, hinting at its role in galactagogue activity.
• Molecular docking and dynamics analysis demonstrate the drug-like properties of the compounds within Breynia patens, targeting multiple receptors.
• The implications of this study highlight the potential of Breynia patens in herbal lactation therapies, needing further clinical investigation.