Systemic inflammatory and thyroid markers for predicting malignancy in indeterminate (Bethesda III–IV) thyroid nodules; could thyroglobulin be a clue? | Synapse
March 3, 2026
Systemic inflammatory and thyroid markers for predicting malignancy in indeterminate (Bethesda III–IV) thyroid nodules; could thyroglobulin be a clue?
Key Points
Malignancy prediction is enhanced with increased thyroglobulin levels in thyroid nodules.
In a cohort of indeterminate thyroid nodules, thyroglobulin was notably associated with cancer risk.
Analysis of Bethesda III–IV thyroid nodules shows the significance of thyroid and inflammatory markers.
This approach highlights the need for further investigation into thyroglobulin's potential diagnostic role.