Background: Emotional distress is often comorbid with serious illness, especially in individuals facing social stigmas, such as patients with HIV. Death acceptance may serve as a protective factor against such distress. Standard psychopharmacologic interventions have shown insufficient results in alleviating distress associated with serious illness. Preliminary research shows psychedelic-assisted therapy to be well-tolerated and a promising novel treatment for various mental health disorders in this population, potentially facilitating death acceptance. However, limited research exists on the intersection of psychedelics, serious illness, and death acceptance, with patients with HIV+ often underrepresented in clinical trials. Objective: This study aims to explore how group psilocybin-assisted therapy may influence attitudes toward death in older long-term AIDS survivor gay men. Design: Transcripts of interviews from a completed parent study were analyzed in this secondary qualitative analysis using Constructivist Grounded Theory. Setting/Subjects: Transcripts from six older, long-term AIDS survivor gay male participants at a medical research institute in the United States were selected for analysis. Results: Three major themes emerged from the data: (1) acceptance of death, dying, or impermanence, (2) acceptance of illness, and (3) embracing complex emotions. The findings suggest group psilocybin therapy may aid participants in fostering death acceptance by accepting their illness and embracing a full spectrum of emotions arising from facing one’s mortality. Conclusion: While further studies are necessary to validate the findings, this secondary analysis contributes to the emerging intersection of psychedelic science and serious illness by incorporating participants’ perspectives, highlighting the importance of concentrating on outcomes related to death acceptance.
Whitmore et al. (Thu,) studied this question.