Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshire Lung Screening Trial

Key Points

• Overall survival rates show no significant difference between populations identified by risk models and those by USPSTF criteria.
• Moderate to severe frailty and multimorbidity were slightly more common in groups identified via risk models compared to USPSTF standards.
• Analysis compared eligibility based on risk factors versus risk scores within the Yorkshire Lung Screening Trial framework.
• Findings highlight that current risk models may not influence survival outcomes, indicating limitations in existing screening strategies.