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Research progress on vasculogenic mimicry in colorectal cancer: mechanisms and therapeutic | Synapse
March 3, 2026
Open Access
Research progress on vasculogenic mimicry in colorectal cancer: mechanisms and therapeutic
JZ
Jian Zewei
ZH
Zhao Haiyan
Key Points
Vasculogenic mimicry enhances tumor progression in colorectal cancer, complicating treatment strategies.
Key evidence shows that vasculogenic mimicry is linked to poor patient outcomes in colorectal cancer.
Assessment of therapeutic interventions suggests flexibility for targeting both angiogenesis and mimicry pathways.
These findings highlight the need for new therapeutic strategies in colorectal cancer, as vasculogenic mimicry may impact treatment efficacy.
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Zewei et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75afbc6e9836116a21833
https://doi.org/https://doi.org/10.1186/s13008-025-00171-z