Cancer-related incomplete intestinal obstruction (CRIO) presents a significant challenge in patients with advanced malignancies, affecting quality of life and complicating treatment regimens. This editorial explores the multifaceted approaches to managing CRIO, emphasizing recent advancements in diagnostic techniques, pharmacological treatments, minimally invasive procedures, and surgical interventions. The pathophysiology of CRIO is complex, involving tumor invasion, fibrosis, and peritoneal dissemination, which result in partial bowel obstruction and impaired motility. Traditional management has focused on supportive care and palliative measures; however, new interventions, such as endoscopic stenting and laparoscopic surgery, have demonstrated improved outcomes with fewer complications. In addition, the integration of systemic therapies like immunotherapy and targeted agents offers promising results in reducing tumor burden and alleviating obstruction. The editorial also discusses the critical role of nutritional support and fluid management in managing CRIO symptoms and improving patient recovery. Despite these advancements, the complexity of CRIO, with its varied causes and patient-specific factors, necessitates individualized, multidisciplinary care strategies. This editorial aims to provide an updated, comprehensive framework for clinicians managing CRIO, highlighting current practices and future directions for research and therapeutic development.
Liu et al. (Tue,) studied this question.