March 3, 2026

A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature

Key Points

The manifestation of clown nose indicates a potential underlying tumor, particularly in metastatic cases.
A 54-year-old man with nasally located nodular lesions had a history of metastatic lung squamous cell carcinoma.
A systematic literature review assessed nodular lesions as a potential sign of tumor metastasis.
This finding highlights the need for awareness of rare clinical signs that may indicate serious underlying malignancies.

Abstract

The "clown nose" is a rare clinical presentation characterized by reddish-brown nodular lesions localized to the nasal tip. This distinctive sign has been associated with metastatic malignancies, genetic syndromes, and primary dermatologic conditions. We describe a rare case of metastatic eccrine porocarcinoma manifesting as a clown nose in a 54-year-old man with a history of metastatic lung squamous cell carcinoma. In addition, we performed a systematic literature review through PubMed to evaluate infiltration of the nose as a potential indicator of underlying tumor metastasis.

Bookmark

A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature

Key Points

Abstract

Cite This Study

Also Consider

Also Consider