Glycine ameliorates aging-related dysfunctions associated with Nmdmc-mediated mitochondrial one-carbon metabolism

Key Points

• Glycine enhances mitochondrial metabolism, leading to a reduction in aging-related dysfunction.
• The findings reveal a significant correlation with biomarkers linked to cellular health and longevity.
• Observational analysis across various age groups highlights the importance of one-carbon metabolism in aging.
• The implications suggest glycine supplementation may boost healthspan but require further investigation in clinical settings.