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Molecular crosstalk between lncRNA H19, miR-29a, and JAK2/STAT3 signaling in alopecia areata: a preliminary study | Synapse
March 3, 2026
Molecular crosstalk between lncRNA H19, miR-29a, and JAK2/STAT3 signaling in alopecia areata: a preliminary study
AE
Aya A. Abd Elghany
ME
Mostafa M. Kamel Eyada
SM
Shymaa A. Maher
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Key Points
Alopecia areata is influenced by the interactions of lncRNA H19 and miR-29a, affecting hair follicle health and immune response.
Expression of lncRNA H19 is linked with significant modulation of miR-29a and JAK2/STAT3 signaling pathways in alopecia areata.
The analysis shows that altered expressions of these molecules may play a critical role in alopecia areata pathogenesis.
Understanding these molecular interactions may lead to new therapeutic strategies for treating alopecia areata.
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Elghany et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b42c6e9836116a22486
https://doi.org/https://doi.org/10.1016/j.cyto.2026.157121
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