A colorimetric DNA chimera biosensor based on bivalent split aptamers and G-quadruplex DNAzyme to detect norfloxacin in seafood

Key Points

• This biosensor detects norfloxacin in seafood, enhancing food safety measures.
• The method shows a detection limit as low as 0.1 µM for norfloxacin in various seafood samples.
• Assessment used a novel colorimetric DNA chimera biosensor based on bivalent split aptamers and G-quadruplex DNAzyme.
• This technique may improve current methods for monitoring antibiotics in food, addressing public health concerns.