CTCF is necessary for development and maintenance of CALM-AF10-induced leukemia

Key Points

• CTCF plays a critical role in maintaining CALM-AF10-induced leukemia.
• Mutation of CTCF severely affects leukemia cell survival and growth.
• Analysis revealed significant disruptions in leukemia progression without CTCF functionality.
• Highlights the importance of CTCF in leukemia research, with potential implications for targeted therapies.