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Testosterone modifies U-Shaped association of eGFR with all-cause mortality in Chinese female centenarians: a prospective cohort study | Synapse
March 3, 2026
Open Access
Testosterone modifies U-Shaped association of eGFR with all-cause mortality in Chinese female centenarians: a prospective cohort study
ZZ
Z. Zhang
Chinese PLA General Hospital
XC
Xiaowei Cheng
ZQ
Zeyu Qu
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Key Points
Testosterone modifies the U-shaped relationship between eGFR and all-cause mortality in female centenarians.
Specifically, centenarians aged over 100 showed notable changes in mortality with varying testosterone levels.
Prospective cohort study assessed thousands of centenarians over a defined time period, focusing on eGFR measurements.
Further exploration of this association may enhance understanding of health outcomes in elderly populations.
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Zhang et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75bd3c6e9836116a23dc9
https://doi.org/https://doi.org/10.1186/s12958-026-01529-w