Repeat Influenza Vaccination Effects in 2021/22 and 2022/23 in a Community-Based Cohort in Hong Kong | Synapse
March 3, 2026Open Access
Repeat Influenza Vaccination Effects in 2021/22 and 2022/23 in a Community-Based Cohort in Hong Kong
Key Points
Repeat influenza vaccination is linked to a notable reduction in titer increase at day 14 post-vaccination, indicating altered immune response.
Titer increase saw a significant decrease, revealing the potential effects of repeated vaccinations on short-term immune reactions.
Assessment of antibody levels indicates minimal changes at six months post-vaccination, highlighting a complexity in long-term immunity.
Findings suggest potential implications for vaccination strategies and the importance of understanding the immune response over time.
Abstract
Our findings suggest that repeated influenza vaccination is associated with reduced titer increase at day 14 post-vaccination, but has less impact on antibody levels at six months post-vaccination.