Assessing Electronic Health Record-Derived Outcomes in a Pragmatic Weight Gain Prevention Trial: Effects, Variability, and Implications for Future Trials

Key Points

• Outcome assessment reveals how electronic health records impact trial results and variability.
• Significant variability may complicate the understanding of weight gain prevention strategies.
• Data variability and sparsity need careful consideration during trial planning and implementation.
• Future trials focusing on electronic health records will benefit from strategies mitigating data sparsity.

Abstract