Medication-related osteonecrosis of the jaw primary prevention: multidomain long-term intervention versus pre-bisphosphonate treatment standalone dental intervention. A retrospective multi-center comparative cohort study

Key Points

• Multidomain dental prevention significantly reduces the incidence of medication-related osteonecrosis of the jaw (MRONJ).
• The intervention involved a long-term protocol, contrasting with a single dental intervention before bisphosphonate therapy.
• This study employed a retrospective multi-center comparative cohort approach to evaluate efficacy.
• Findings suggest that integrating routine dental evaluations into cancer care pathways may enhance patient safety.