Cationic donor–π–acceptor AIEgen enabling dual-mode reactive oxygen species generation for antibacterial photodynamic therapy | Synapse
March 3, 2026
Cationic donor–π–acceptor AIEgen enabling dual-mode reactive oxygen species generation for antibacterial photodynamic therapy
Key Points
Type I and II reactive oxygen species are generated under white light, supporting efficient antibacterial activity.
A cationic D-π-A AIE-active photosensitizer demonstrated effectiveness in eradicating Staphylococcus aureus.
This approach offers a novel photodynamic therapy method using rapid imaging capabilities.
Dual-mode generation of reactive oxygen species highlights potential for improved antibacterial treatments.
Abstract
A cationic D-π-A AIE-active photosensitizer was designed to efficiently generate type I/II ROS under white light, enabling rapid imaging and photodynamic eradication of Staphylococcus aureus.