IgG4-Positive Ocular Adnexal Extranodal Marginal Zone Lymphoma as an Aggressive Clinical Subtype: Evidence From a 377-Patient Cohort

Key Points

• IgG4-positive ocular adnexal extranodal marginal zone lymphoma presents a notable aggressive clinical phenotype.
• Out of 377 patients, a significant portion exhibited adverse outcomes associated with this subtype.
• Observational analysis across a large cohort indicates the need for focused biomarkers to tailor treatment strategies.
• Findings emphasize potential differences in management approaches to address this aggressive lymphoma subtype.