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Correction: 4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1 | Synapse
March 3, 2026
Open Access
Correction: 4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1
LL
L. L.
GF
Guobin Fu
JW
Jing Wu
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Key Points
Lung adenocarcinoma metastasis is significantly suppressed by 4-cholesten-3-one, highlighting its potential therapeutic role.
Key proteins impacted include translocation of HMGB1, HIF1α, and Caveolin-1 with significant implications for tumor behavior.
Assessment utilizing cellular and molecular assays demonstrated robust regulation of metastasis-linked pathways by 4-cholesten-3-one.
Results suggest that targeting these pathways may become a novel approach to lung adenocarcinoma treatment.
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L. et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75ccdc6e9836116a25fc9
https://doi.org/https://doi.org/10.1038/s41419-025-08408-z