March 3, 2026Open Access

Sex-Dependent Microbial and Host Profiles Following Fecal Microbiota and Bifidobacterium longum Treatment in Stress-Induced Gut Dysbiosis

Key Points

Microbial and host profiles differ significantly based on sex following treatment for gut dysbiosis.
Key metrics show that sex is a crucial biological variable affecting treatment outcomes in IBS models.
Assessment used targeted microbiota therapies in a stress-induced gut dysbiosis model to analyze responses.
Implications suggest personalized microbiome-based treatments may improve therapeutic outcomes for IBS patients.

Abstract

These findings highlight sex-specific microbial and host responses to microbiota-targeted therapies in a stress-induced IBS model, emphasizing sex as a biological variable in designing personalized microbiome-based treatments.

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Cite this study

Song et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75ce2c6e9836116a261fb — DOI: https://doi.org/10.5009/gnl250440

Authors

Chin-Hee Song

Nayoung Kim

Seoul National University

Ryoung Hee Nam

Seoul National University Bundang Hospital

Journals

Gut and Liver

Actions

Institutions

Seoul National University

Seoul National University Bundang Hospital

Bank of Korea

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Sex-Dependent Microbial and Host Profiles Following Fecal Microbiota and Bifidobacterium longum Treatment in Stress-Induced Gut Dysbiosis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion