Correction: DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway | Synapse
March 3, 2026Open Access
Correction: DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway
Key Points
Cisplatin resistance is promoted by DNAJC5 through autophagy mechanisms, indicating a significant role in ovarian cancer.
Key evidence shows that inhibition of the BiP/IRE1α/XBP1 pathway decreases resistance levels in cancer cells.
Analysis focused on epithelial ovarian cancer cell lines, demonstrating the involvement of crucial molecular pathways.
These findings highlight potential new strategies for overcoming treatment resistance and improving patient outcomes.