Cryo-printed collagen scaffolds reinforced with dentin-derived bioactive particles promote osteo-angiogenic bone regeneration

Key Points

• Cryo-printed collagen scaffolds significantly enhance osteo-angiogenic bone regeneration.
• Collagen scaffolds embedded with dentin-derived bioactive particles show a marked increase in osteogenesis and angiogenesis.
• Assessment through in vitro and in vivo techniques reveals the scaffolds' efficacy in supporting bone healing processes.
• The findings support the potential for using advanced bioactive materials in regenerative medicine strategies.