CRISPR/Cas9 and reproductive failure: applications, ethical challenges, and future perspectives in human germline genome editing

Key Points

• Germline editing with CRISPR/Cas9 presents ethical challenges that impact reproductive failure risk.
• Key ethical concerns include potential unintended consequences from genome editing on future generations.
• The discussion addresses potential applications of CRISPR/Cas9 in overcoming reproductive failures seen in clinical settings.
• Highlights the need for comprehensive ethical frameworks to guide the responsible use of genome editing technologies.